Fisher B, Costantino JP, Wickerman L, et al
10.1007/s00213-014-3664-5 38 FriesG
Overall, many had meaningful weight loss, but some individual results varied, according to the Cleveland Clinic: "Those treated for obesity lost an average of 8.4% of body weight before discontinuation and regained an average of 0.5% one year later Those treated for type 2 diabetes lost an average of 4.4% of body weight before discontinuation and lost an additional 1.3% of body weight one year later In the obesity group, 55% gained weight in the year after discontinuation, while 45% kept losing or stayed the same In the diabetes group, 44% gained weight, while 56% kept losing or stayed the same" There were two primary issues that led to patients stopping the medication, which were cost or insurance coverage, and side effects
For most patients, GLP-1 medications are generally safe and well-tolerated, but like any medication, they can have side effects such as nausea, vomiting, diarrhea, or constipation
Slower Gastric Emptying Because tirzepatide slows down the movement of food through your stomach, it can make it harder for you to take oral medications for COVID-19, such as pain relievers or antiviral treatments
